The Summary A Chinese led research team say a blood test – called PanSeer – detects cancer in 95% of asymptomatic individuals who later receive a diagnosis. “We demonstrated that five types of cancer can be detected through a DNA methylation-based blood test up to four years before conventional diagnosis,” the team writes in the… Continue reading ‘Liquid Biopsy’ Detects Cancer Years Before Symptoms
Covid-19 infections keep rising inexorably. So do Covid-10 publications. Impossible to keep up with the data overload but the following articles have caught my eye. If you have read some other noteworthy ones, do let me know. My selection includes a considered opinion on the management of acute respiratory distress syndrome ARDS, promising Phase 1… Continue reading Covid-19 Digest 19 July
*Updated on 25 July 2020 with addendum The above picture shows a red blood cell (RBC) cast in a picture shared by Jay R Seltzer MD, Chief of Nephrology at Missouri Baptist, St Louis, USA. He has a special interest in urine microscopy and shares his beautiful pictures on Twitter as as @jrseltzer. This RBC… Continue reading Pic of the Day 2
The eagle eyed amongst you may have noticed a little feature on the front page of this website: Mauritius in Scientific Publications. This is where the most recent five publications on Pubmed is listed. When I set it up a few weeks ago, I didn't expect new items to appear that often. There has actually… Continue reading First Covid-19 Publications Made in Moris!
Big announcement from Bayer on Thursday 9 June. Are we on the verge of a major step forward in the pharmacological fight against diabetic nephropathy? We all know diabetic nephropathy (DN) is by far the most common cause of end-stage renal disease in Mauritius and worldwide. The inhibition of the renin-angiotensin-aldosterone system (RAAS) has been… Continue reading A Fine Renal Breakthrough?
Twitter is curiously ignored here in Mauritius. In our collective consciousness, Twitter is the preserve of the loose cannon insomniac president, the vainglorious bitchy celebs and the excitable political hacks. Maybe it is too frenetic for our laidback populace. Certainly, too barren for any reasoned medical discourse I thought. A 140 character limit! During a… Continue reading The Art and Science of Tweeting in Colour
Do you think you got enough sleep this past week? Can you recall the last time you woke up without an alarm clock feeling refreshed, not needing caffeine? If the answer to either of these questions is "no", you are not alone. Two-thirds of adults throughout all developed nations fail to obtain the recommended eight… Continue reading Sleep and Sleep Webinar Series
(Picture from Talish et Al, NEJM 2020) I consider myself as a long practising nephrologist but I must admit I had never heard of or seen uraemic stomatitis until the case report in the New England Journal of Medicine in the last week. To make up for it, I looked up all case reports in… Continue reading A Review of Uraemic Stomatitis
This is the second post in series of nephrology nomenclature. Check the first one here. What is the KDIGO? The Kidney Disease: Improving Outcomes is a wonderful example of American multilateralism. In 1950, the National Nephrosis Foundation was set up by the desperate attempts of the parents of a diseased child. Renamed The National Kidney Foundation… Continue reading KDIGO: Putting the K in Nephrology Nomenclature
Any budding nephrologist here? Do you know what you are letting yourself in? Most kidney diseases not have only a late and insidious onset but also have vague generalized symptoms shared with numerous other diseases (nausea, loss of appetite, fatigue, breathlessness and peripheral oedema for example). None of these permit the general public to localize… Continue reading Nonplussing nephrological nomenclature: nothing new